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There are several unique weapons in Fallout: New Vegas, weapons of which only one exists in the game world (with some exceptions). Some are found in specific locations while others are obtained as quest rewards.

Unarmed weapons[]

Weapon Variant of Location
Cram Opener Bladed gauntlet Carried by Little Buster in Camp McCarran. If one completes the quest Three-Card Bounty for Major Dhatri, Little Buster will leave the camp and go to Freeside, via the north gate. After one or two in-game days, his corpse can be found near the entrance's railroad tracks by the Old Mormon Fort.
Dr. Klein's glove² Old World Blues (add-on) Scientist glove Found at Higgs Village in house #101 upstairs, in the middle room upstairs. The glove is in the bottom corner of a cabinet to the right side of the door.
Dr. Mobius' glove² Old World Blues (add-on) Scientist glove Found near Dr. Mobius in the Forbidden Zone dome, lying on a table immediately to the left of the center stairs, next to some of Dr. Mobius' work.
Embrace of the Mantis King! (GRA) Gun Runners' Arsenal Mantis gauntlet Purchased from Mick at Mick & Ralph's in Freeside, or the Vendortron at Gun Runners if Mick is dead.
Fist of Rawr Lonesome Road (add-on)
Fist of the North Rawr Wild Wasteland
Unique Made at a workbench with Rawr's Talon, found on the body of Rawr in a cave in The Divide.
Golden Gloves Boxing gloves Found on the casino floor of the Lucky 38 casino, on a bookshelf behind the bar in the VIP Lounge. The lounge is situated at the top of a small staircase to the left upon entering the Lucky 38.
Greased Lightning² Gun Runners' Arsenal Power fist Purchased from Torres at Hidden Valley, or the Vendortron at Gun Runners if Torres is dead.
Love and Hate¹ Spiked knuckles Carried by a Viper Gang leader at Bonnie Springs.
Paladin Toaster Zap glove Found in Black Rock cave, on the body of a dead prospector.
Pushy Displacer glove Found in Ruby Hill Mine, on the body of a dead Jackal gang member lying near the dry tunnel entrance in the underground lake area.
Recompense of the Fallen Dog tag fist Found in Aurelius of Phoenix's desk, in his office at Cottonwood Cove.
Salt-Upon-Wounds' power fist² Honest Hearts Power fist Found in the reward footlocker after completing Honest Hearts and receiving either the "May my Hand Forget its Skill" or "O Daughter of Babylon" achievement/trophy. It may also be obtained if the player character loots Salt-Upon-Wounds before the ending sequence.
She's Embrace² Honest Hearts Yao guai gauntlet Obtained from White Bird upon completion of the quest "Rite of Passage."
Two-Step Goodbye²
Gun Runners' Arsenal
Ballistic fist Purchased from the Vendortron at Gun Runners.
¹ Normal holdout weapon: May be concealed regardless of Sneak skill.
² Improved holdout weapon: May be concealed if Sneak is equal to or higher than 50.

Melee weapons[]

Weapon Variant of Location
Blade of the East Bumper sword Carried by Legate Lanius in the final battle if siding with the NCR, Yes Man, or House.
Blood-Nap² Lonesome Road (add-on) Bowie knife Found in The Courier's Mile. This weapon becomes accessible only after first completing The Launch. It is found sticking out of a street lamp just to the left as one enters the area.
Broad machete Courier's Stash Machete Appears in the player character's inventory with the Courier's Stash add-on or with the Classic Pack.
Chance's knife² Combat knife Found in Chance's grave, north of Goodsprings on a hill near tribal village.
Chopper² Cleaver Found at Wolfhorn ranch, inside the farmhouse on the stove on the right wall of the house.
Figaro¹ Straight razor Carried by Sergio inside The King's School of Impersonation.
Gehenna Gun Runners' Arsenal Shishkebab Purchased from the Vendortron at Gun Runners.
Knock-Knock Fire axe Found in Camp Searchlight's fire station. One must first obtain the key from Logan.
Liberator Machete Carried by Dead Sea at Camp Nelson. Obtained either by completing the quest We Are Legion or by looting his corpse.
Nephi's golf driver 9 iron Carried by Driver Nephi, a Fiend to the southwest of New Vegas.
Nuka-Breaker Gun Runners' Arsenal Rebar club Purchased from Mick at Mick & Ralph's in Freeside, or from the Vendortron at Gun Runners if Mick is dead.
Oh, Baby! Super sledge Found in Charleston Cave, in the far southwest open area of the cave, accessible via tunnels from the north and east. It is lying on the ground near the west wall, directly west of the eastern tunnel entrance.
Old Glory Lonesome Road (add-on) Pool cue Carried by Ulysses, it also appears in Ulysses' footlocker upon the completion of Lonesome Road.
The Humble Cudgel Lead pipe Found on the corpse of a dead prospector in the sealed sewers, which is accessed with the key from "blind" Luke in the Central sewers.
X-2 antenna Old World Blues (add-on) Unique Found on top of the satellite dish, at the X-2 transmitter antenna array.
¹ Normal holdout weapon: May be concealed regardless of Sneak skill.
² Improved holdout weapon: May be concealed if Sneak ≥ 50.

Guns[]

Weapon Variant of Location
A Light Shining in Darkness² Honest Hearts .45 Auto pistol Carried by Joshua Graham, it also appears in a footlocker at the Southern passage in Zion Canyon after completion of the Honest Hearts main quest.
Abilene Kid LE BB gun BB gun Found in Fields' shack, south-west of Nellis Air Force Base, sitting on one of the shelves on the left wall.

Wild Wasteland With the Wild Wasteland trait, it will instead be found inside of Jimmy's well. The well appears in front of the shack after talking to Rex upon him saying "aroo" and asking him if someone fell down a well.

All-American³ Marksman carbine Found on an overturned table on the right side of the Vault 34 armory.
Big Boomer Sawed-off shotgun Carried by Old Lady Gibson in the Gibson scrap yard.
Bozar³ Gun Runners' Arsenal Light machine gun Purchased from the Vendortron at Gun Runners.
Christine's CoS silencer rifle³ Old World Blues (add-on) Sniper rifle Found leaning against the wall in a corner of a crumbling building outside the north wall of Little Yangtze.
CZ57 Avenger Minigun Found inside a blue truck located in the center The Devil's Throat, next to the body of a dead prospector.
Dinner Bell Hunting shotgun Obtained from Red Lucy in The Thorn, after completing the quest Bleed Me Dry.
Gobi Campaign scout rifle³ Sniper rifle Found in a locked gun case (Very Hard/Lockpick 100) at the Sniper's nest.
La Longue Carabine Cowboy repeater Carried by Corporal Sterling at Camp McCarran. If the quest Three-Card Bounty has been completed, he will move to Camp Forlorn Hope.
Li'l Devil¹ Gun Runners' Arsenal 12.7mm pistol Purchased from Mick at Mick & Ralph's in Freeside, or from the Vendortron at Gun Runners if Mick is dead.
Lucky² .357 Magnum revolver Found in a locked floor safe (Hard/Lockpick 75) on the first floor of the Bison Steve Hotel in Primm.
Maria² 9mm pistol Carried by Benny in The Tops or The Fort if Benny was not killed in Ring-a-Ding-Ding!.
Medicine Stick Gun Runners' Arsenal Brush gun Purchased from the Vendortron at Gun Runners.
Mysterious Magnum² .44 Magnum revolver Carried by the Lonesome Drifter, at the Sunset Sarsaparilla billboard next to the highway just east of El Dorado dry lake and north of the El Dorado Gas & Service, it can also be acquired by passing a barter check of 50 during the quest Talent Pool.
Paciencia Gun Runners' Arsenal Hunting rifle Purchased from Cliff Briscoe at the Dino Bite gift shop in Novac, or from the Vendortron at Gun Runners if Cliff is dead.
Ratslayer³ Varmint rifle Found inside Broc flower cave, below a desk in the makeshift laboratory on the upper level.
Sleepytyme² Gun Runners' Arsenal 10mm SMG Purchased from the Vendortron at Gun Runners.
Sturdy caravan shotgun Courier's Stash Caravan shotgun Appears in the player's inventory when the Courier's Stash add-on or the Classic Pack pre-order pack is installed and detected by the game.
Survivalist's rifle Honest Hearts Service rifle Found at the Red Gate in a duffle bag marked "The Survivalist's Duffle Bag" next to Randall Clark's skeleton.
That Gun 5.56mm pistol Found in Novac, inside the Dino Bite gift shop. It can either be purchased from Cliff Briscoe, or stolen from the storage room.
This Machine Battle rifle Obtained at the end of the unmarked quest Dealing with Contreras, either by Daniel Contreras if he isn't turned in, or by Carrie Boyd if he is.
Vance's 9mm SMG 9mm SMG Missing from a display case in the Vikki and Vance Casino, Primm Slim will reveal (Science 50) that the weapon can be found in a locked safe (Very Hard/Lockpick 100) at Wins hideout. The lock can be picked, or with a high enough speech skill (55) you can convince the Wins to give you the combination, or if you don't have enough speech for the speech check talk to Sammy again and another dialog option will appear.
Weathered 10mm pistol Courier's Stash 10mm pistol Appears in the player's inventory when the Courier's Stash add-on or the Classic Pack pre-order pack is installed and detected by the game.
¹ Normal holdout weapon: May be concealed regardless of Sneak skill.
² Improved holdout weapon: May be concealed if Sneak ≥ 50.
³ Scoped by default.

Energy weapons[]

Weapon Variant of Location
AER14 prototype Laser rifle Found on the fifth floor (pest control) of Vault 22, through the locked (varies by player level) stairway door to the common area, lying on the ground next to a scorched skeleton.
Alien blaster Wild Wasteland Unique Carried by the alien captain, at the Mercenary camp just north of Horowitz farmstead. (Can only be obtained if the Wild Wasteland trait is chosen.)
Cleansing Flame Gun Runners' Arsenal Flamer Purchased from Gloria Van Graff at the Silver Rush in Freeside, or from the Vendortron at Gun Runners if Gloria is dead.
Compliance Regulator¹ Honest Hearts Laser pistol Found in Fallen Rock cave, in the room with a reloading bench and a terminal, hidden behind an open wooden box.
Elijah's jury-rigged Tesla cannon Old World Blues (add-on) Tesla cannon Found in the Big MT, west of the wooden platform where the second sentry gun is located at Elijah's Watch.
Euclid's C-Finder Unique Obtained from Max in Freeside, outside of Mick & Ralph's.
Holorifle² Dead Money Unique Obtained at the beginning of Dead Money from Elijah.
MF Hyperbreeder Alpha¹ Gun Runners' Arsenal Recharger pistol Purchased from Cliff Briscoe at the Dino Bite gift shop in Novac, or from the Vendortron at Gun Runners if Cliff is dead.
Missing laser pistol Laser pistol Found in scorpion gulch on a large rock in the middle of the gulch, next to the corpse of a wastelander during the unmarked quest Pistol Packing.
Pew Pew¹ Laser pistol Found next to the body of Allen Marks at the Sunset Sarsaparilla headquarters after presenting at least 50 Sunset Sarsaparilla star bottle caps to Festus during A Valuable Lesson.
Pulse gun Unique Found inside a locked chest in the Vault 34 armory. The door to the armory must be unlocked using the terminal in the Overseer's office. The chest can be opened with a Lockpick skill of 100, or with Col. Blackwell's key found in a filing cabinet in Pearl's barracks at Nellis Air Force Base.
Q-35 matter modulator Plasma rifle Found in REPCONN headquarters, behind a locked (Very Hard/Lockpick 100) door. This door can also be opened with a level 3 REPCONN HQ keycard. There is also a wall terminal (100 Science to hack) next to the door that can also be used.
Sprtel-Wood 9700 Gun Runners' Arsenal Gatling laser Purchased from Gloria Van Graff at the Silver Rush in Freeside, or from the Vendortron at Gun Runners if Gloria is dead.
Tesla-Beaton prototype Tesla cannon Found at the Crashed vertibird next to a skeleton, near the old nuclear test site far southeast.
The Smitty Special Gun Runners' Arsenal Plasma caster Purchased from Gloria Van Graff at the Silver Rush in Freeside, or from the Vendortron at Gun Runners if Gloria is dead.
Van Graff laser rifle Laser rifle Obtained at the Silver Rush during the quest Birds of a Feather when given the choice between a plasma rifle or a laser rifle.
Van Graff plasma rifle Plasma rifle Obtained at the Silver Rush during the quest Birds of a Feather when given the choice between a plasma rifle or a laser rifle.
YCS/186² Gauss rifle Carried by a mercenary at the Mercenary camp east of Brooks tumbleweed ranch. (Cannot be acquired if the player has chosen the Wild Wasteland Trait, as it will be replaced by the alien blaster.)
¹ Improved holdout weapon: May be concealed if Sneak ≥ 50.
² Scoped by default.

Explosive weapons[]

Weapon Variant of Location
Esther Gun Runners' Arsenal Fat Man Purchased from the Vendortron at Gun Runners.
Great Bear grenade rifle Lonesome Road (add-on) Grenade rifle Found in a gun-case located near Colonel Royez in the Long 15.
Red Victory grenade rifle Lonesome Road (add-on) Grenade rifle Found in a gun case at Dry Wells, on a cliff overlooking the encampment.
Mercenary's grenade rifle Courier's Stash Grenade rifle Appears in the player's inventory when the Courier's Stash add-on or the Classic Pack pre-order pack is installed and detected by the game.
Thump-Thump Grenade rifle Found next to two broken generators inside Nellis array during Ant Misbehavin'.
Mercy Grenade machinegun Found by a dead Brotherhood of Steel soldier at Dead Wind Cavern.
Annabelle Missile launcher Carried by the nightkin sniper on the radio tower catwalk at Black Mountain.
Holy Frag Grenade Wild Wasteland Frag grenade Found in the basement of the church in the eastern part of Camp Searchlight. (Must have Wild Wasteland trait)
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