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MEIS2

From Wikipedia, the free encyclopedia
MEIS2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMEIS2, HsT18361, MRG1, Meis homeobox 2, CPCMR
External IDsOMIM: 601740; MGI: 108564; HomoloGene: 7846; GeneCards: MEIS2; OMA:MEIS2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 15: 36.89 – 37.1 MbChr 2: 115.69 – 115.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Homeobox protein Meis2 is a protein that in humans is encoded by the MEIS2 gene.[5][6]

This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000134138Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027210Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Smith JE, Afonja O, Yee HT, Inghirami G, Takeshita K (Jan 1998). "Chromosomal mapping to 15q14 and expression analysis of the human MEIS2 homeobox gene". Mamm Genome. 8 (12): 951–2. doi:10.1007/s003359900621. PMID 9383298. S2CID 20187903.
  6. ^ a b "Entrez Gene: MEIS2 Meis homeobox 2".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.