Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Electrical stimulation of astrocytes using electrodes coated with graphene oxide and reduced graphene oxide can be used to trigger specific calcium signals.
Selective and quasi-continuous ferroelectric switching has been successfully implemented in devices based on topological Chern insulators, enabling the realization of 1,280 ferroelectric states for a proof-of-concept demonstration in noise-immune neuromorphic computing.
This work reports core–shell photovoltaic nanocells to enhance the photoresponse of the active layer and realize photolithographic manufacturing of large-scale-integrated organic phototransistors for high-resolution biomimetic vision.
Mirror twin boundaries in monolayer MoS2—line defects with reflection-mirroring symmetry—are one-dimensionally metallic. In this work, the authors fabricate these mirror twin boundary networks by epitaxity and incorporate them into ultrascaled 2D transistor circuits as gate electrodes.
An optimized design of free-space silicon nanoantennas combines high quality factor and low mode volume, reducing the trade-off between these parameters.
A highly tunable Nernst effect has been demonstrated in graphene/indium selenide devices, achieving a record Nernst coefficient at ultralow temperatures, highlighting its potential for quantum technologies and low-temperature applications.
Minimally invasive cellular-level target-specific neuromodulation is needed to decipher brain function and neural circuitry. Here nano-magnetogenetics using magnetic force actuating nanoparticles has been reported, enabling wireless and remote stimulation of targeted deep brain neurons in freely behaving animals.
Here the authors present a pH-sensitive DNA origami nanoswitch that hides ligands for death receptors and displays them as a cytotoxic hexagonal pattern in acidic tumour microenvironments. This reduces tumour growth in a murine model of breast cancer with minimal on-target, off-tumour toxicity.
A one-pot kinetically controlled synthetic framework for constructing regioselective architectures in a series of well-defined metallic heterostructures is demonstrated, in which phase and morphology regulation of Pd–Sb substrate are implemented to validate the kinetically controlled synthesis.
Simulations show that two-dimensional-material-based static random-access memory (SRAM) circuits leverage their low parasitic capacitance, counteracting performance declines due to increased interconnect resistance and potentially surpassing Si-based SRAM in terms of both performance and energy efficiency at advanced technology nodes.
Targeted black phosphorus nanosheet-based therapeutics that efficiently deliver resolvin D1 to lesional macrophages for the treatment of atherosclerosis by reducing oxidative stress and resolving inflammation have been discussed.
Inactivating hyperregulated metabolic pathways in cancer is used in the clinic to slow cancer progression. Here the authors show that l-tyrosine can reactivate melanogenesis in melanoma cells, resulting in suppression of cancer growth and production of melanin, which can be used as an additional photothermal therapy agent for melanoma eradication.
The progression of neurological disorders might be influenced by environmental factors. Here the authors show that exposure to polystyrene nanoparticles leads to aggregation of the protein TDP-43, which is involved in amyotrophic lateral sclerosis (ALS), triggering ALS-like symptoms in animal models.
By combining fibre-based trapping and position detection with cold damping through planar electrodes, cooling of a silica nanoparticle particle motion to a few hundred phonons on a chip is achieved.
Multiwalled boron nitride nanotubes, featuring coherently stacked structures with monochirality, homo-handedness and unipolarity among the component tubes, show a large nonlinear chiroptical response.
Ischaemic heart disease, which poses a severe threat to human health, is characterized by mitochondria damage and energy metabolism disorder. Here mitochondria were orally transplanted to the heart using nanomotors to restore energy metabolism by non-invasive administration.
This paper presents a virus-like lipid nanoparticle decorated with spike proteins capable of carrying antigens, including mRNA and proteins, for vaccination against SARS-CoV-2 variants.
The ability to genetically modify haematopoietic stem cells would allow the durable treatment of a diverse range of genetic disorders but gene delivery to the bone marrow has not been achieved. Here lipid nanoparticles that target and deliver mRNA to 14 unique cells within the bone marrow are presented.
FRETfluors—nanostructures with Cy3 and Cy5 dyes and a DNA scaffold—are used to generate distinct spectroscopic signals from different configurations and mixtures of mRNA, dsDNA and proteins in an anti-Brownian electrokinetic trap for single-molecule multiplexed sensing.