narratively i think the institute should have known about or concerned themselves with the Cabot House in some way, not only does Jack Cabot understand science and many more things, but he could be quite valuable to the institute for other things and the institute could be valuable to him as well, and yet he has no relation to the institute in any way or any objects taken and repurposed and used by him, like in the form of institute technology, which i find so bizzar because the institute have literal spies all over the commonwealth in the form of synth humans and animals alike.
and you would have thought maybe they would not only know about him and his research but also possibly wanted to know his secrets to his eternal life serum and might want to use that serum in some manner to use for their synths or for themselves in some way.
but narratively it's like the Cabot house is nonexistent to the institute's radar as a whole for some unknown reason, i mean the institute constantly seek out people with talents in knowledge all the time, you would think they would become curious in some manner with this guy's existence somehow and maybe try to either help him or perhaps do some kind of trade in knowledge for knowledge, you would think they would be helping each other in some way right?