Featured
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Correspondence |
Forensics: experts disagree on statistics from DNA trawls
- Charles Taylor
- & Paul Colman
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Letter |
Tracking G-protein-coupled receptor activation using genetically encoded infrared probes
Rhodospsin is a G-protein-coupled receptor that is responsible for vision in dim light. Light isomerizes the protein's retinal chromophore and triggers concerted movements of several transmembrane helices. Here, an approach involving mutant rhodopsins and infrared spectroscopy enabled changes in the electrostatic environment to be seen as rhodopsin proceeded along its activation pathway. Early conformational changes were observed that precede the well-known larger movements of the transmembrane helices.
- Shixin Ye
- , Ekaterina Zaitseva
- & Reiner Vogel
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News |
Fossil finger points to new human species
DNA analysis reveals lost relative from 40,000 years ago.
- Rex Dalton
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Research Highlights |
Palaeontology: Egg-stracting DNA
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News Feature |
Science in court: DNA's identity crisis
It may be the gold standard of forensic science, but questions are now being raised about DNA identification from ever-smaller human traces. Natasha Gilbert asks how low can you go?
- Natasha Gilbert