Extended Data Fig. 1: Experimental setup of MMG apparatus and electron microscope image of m-Torquer for wireless neuromodulation in vivo.
From: In vivo magnetogenetics for cell-type-specific targeting and modulation of brain circuits
(a) General components of MMG apparatus. The system consists of a rotational magnetic force generator (MFG), an Arduino controller, and a user interface system. (b) Photographs showing top and side views of MMG apparatus of different bore diameters. The 16-cm, 35-cm, and 70-cm MMG apparatus are designed for cell-based experiments, in vivo studies of a single mouse, and in vivo large-area behavioral studies of multiple animals, respectively. Scale bars, 5 cm. (c) 3D illustrations of 16-, 35-, and 70-cm MMG apparatus showing the configuration of the magnetic arrays, including the numbers, dimensions, positions, and angles of magnets. (d) Dynamic changes of the magnitudes of x-component (Bx), y-component (By), and combined total (Btotal) magnetic field. (e) SEM image of an m-Torquer. The 200 nm m-Torquer is composed of assembled monolayer octahedral magnetic nanoparticles on spherical support via click chemistry. Scale bar, 100 nm.