Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex (Q63379240)

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4 May 2020

title

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex (English)

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4 May 2020

author

Panagis Filippakopoulos

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4 May 2020

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4 May 2020

Evelyne Lima-Fernandes

object named as

Evelyne Lima-Fernandes

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Jack Greenblatt

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4 May 2020

Danton Ivanochko

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4 May 2020

Levon Halabelian

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4 May 2020

Elizabeth Henderson

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4 May 2020

Pavel Savitsky

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4 May 2020

Harshika Jain

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4 May 2020

Edyta Marcon

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4 May 2020

Shili Duan

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4 May 2020

Ashley Hutchinson

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4 May 2020

Alma Seitova

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4 May 2020

Dalia Barsyte-Lovejoy

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language of work or name

English

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publication date

1 February 2019

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4 May 2020

published in

Nucleic Acids Research

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4 May 2020

volume

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issue

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4 May 2020

page(s)

1225-1238

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Creative Commons Attribution-NonCommercial 4.0 International

4 May 2020

start time

20 November 2018

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April 2022 Public Data File from Crossref

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6379669/fullTextXML

inferred from PubMed Central ID database lookup

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PRDM5 is silenced in human cancers and has growth suppressive activities

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Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP

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FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1.

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Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells

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Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

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NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex

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Expression and prognostic significance of different mRNA 5'-end variants of the oncogene EVI1 in 266 patients with de novo AML: EVI1 and MDS1/EVI1 overexpression both predict short remission duration

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High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated.

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Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

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Myeloid transforming protein Evi1 interacts with methyl-CpG binding domain protein 3 and inhibits in vitro histone deacetylation by Mbd3/Mi-2/NuRD

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High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities

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Features and development of Coot

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The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis

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Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

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12 December 2020

Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex

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Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells

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c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex

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Histone methylation by PRC2 is inhibited by active chromatin marks

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Cancer biology and NuRD: a multifaceted chromatin remodelling complex

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NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

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Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors

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The Prdm family: expanding roles in stem cells and development

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Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

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How good are my data and what is the resolution?

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Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia

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EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation

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The structure of the core NuRD repression complex provides insights into its interaction with chromatin.

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PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase

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PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity

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Identifiers

DOI

10.1093/NAR/GKY1192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30462309%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

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4 May 2020

PubMed publication ID

30462309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30462309%20AND%20SRC:MED&resulttype=core&format=json