Human mediator subunit MED26 functions as a docking site for transcription elongation factors (Q24310867)

Ronald C Conaway

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Shigeo Sato

Shigeo Sato

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Tari J Parmely

Tari J Parmely

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Skylar A Martin-Brown

Skylar Martin-Brown

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Chris Seidel

Chris W Seidel

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Chengqi Lin

Chengqi Lin

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Hidehisa Takahashi

Hidehisa Takahashi

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author name string

Charles A S Banks

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Stephanie E Kong

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Henrietta Szutorisz

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Edwin R Smith

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

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language of work or name

English

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publication date

8 July 2011

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published in

Cell

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volume

146

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issue

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page(s)

92-104

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cites work

1 reference

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Misguided transcriptional elongation causes mixed lineage leukemia

19 March 2017

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CDK8 is a stimulus-specific positive coregulator of p53 target genes

19 March 2017

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Controlling the elongation phase of transcription with P-TEFb

19 March 2017

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Ras induces mediator complex exchange on C/EBP beta

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NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

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A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

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19 March 2017

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A chromatin landmark and transcription initiation at most promoters in human cells

19 March 2017

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Progression through the RNA polymerase II CTD cycle

7 April 2017

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RNA polymerase is poised for activation across the genome

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HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP

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HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription

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Cyclin-dependent kinase 8 positively cooperates with Mediator to promote thyroid hormone receptor-dependent transcriptional activation

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II

27 September 2017

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Complexity in transcription control at the activation domain-mediator interface

27 September 2017

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Postrecruitment regulation of RNA polymerase II directs rapid signaling responses at the promoters of estrogen target genes

27 September 2017

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27 September 2017

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Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

27 September 2017

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Transcription regulation through promoter-proximal pausing of RNA polymerase II.

27 September 2017

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YY1 functions with INO80 to activate transcription

27 September 2017

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Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL.

27 September 2017

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27 September 2017

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Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA.

27 September 2017

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Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions

27 September 2017

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Mediator requirement for both recruitment and postrecruitment steps in transcription initiation

27 September 2017

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Transcription Factor and Polymerase Recruitment, Modification, and Movement on dhsp70 In Vivo in the Minutes following Heat Shock

27 September 2017

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Novel critical role of a human Mediator complex for basal RNA polymerase II transcription

27 September 2017

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P-TEFb kinase recruitment and function at heat shock loci

27 September 2017

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A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor delta from rat liver

27 September 2017

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Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock

27 September 2017

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Refinements to label free proteome quantitation: how to deal with peptides shared by multiple proteins

30 May 2018

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Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS.

29 November 2018

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Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes

29 November 2018

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Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9

29 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21729782

12 December 2020

inferred from PubMed ID database lookup

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A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection

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An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

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Analyzing chromatin remodeling complexes using shotgun proteomics and normalized spectral abundance factors

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DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics

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Statistical Analysis of Membrane Proteome Expression Changes inSaccharomycescerevisiae

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Large-scale analysis of the yeast proteome by multidimensional protein identification technology

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Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.

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Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

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Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

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Proteomic Analysis by Multidimensional Protein Identification Technology

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

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Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

21729782

1 reference