DNA nanostructures articles within Nature

Featured

  • Article |

    A method is presented to harness the paper-folding mechanism of reconfigurable macroscale systems to create reconfigurable DNA origami structures, in anticipation that it will advance the development of complex molecular systems.

    • Myoungseok Kim
    • , Chanseok Lee
    •  & Do-Nyun Kim
  • Article
    | Open Access

    The authors introduce a single-molecule DNA-barcoding method, resolution enhancement by sequential imaging, that improves the resolution of fluorescence microscopy down to the Ångström scale using off-the-shelf fluorescence microscopy hardware and reagents.

    • Susanne C. M. Reinhardt
    • , Luciano A. Masullo
    •  & Ralf Jungmann
  • Letter |

    Probing the assembly process that occurs when single-stranded DNA is folded into desired shapes by ‘DNA origami’ shows that it can be guided by controlling the strengths of local and long-range interactions, enabling more reproducible synthesis.

    • Katherine E. Dunn
    • , Frits Dannenberg
    •  & Jonathan Bath
  • Letter |

    A general method of folding arbitrary polygonal digital meshes in DNA uses a routeing algorithm based on graph theory and a relaxation simulation that traces scaffold strands through the target structures to produce complex structures with an open conformation that are stable under biological assay conditions.

    • Erik Benson
    • , Abdulmelik Mohammed
    •  & Björn Högberg