Collection 

Translational circadian research

Submission status
Open
Submission deadline

In 2017, the description of the core circadian timekeeping system won the Nobel Prize in Medicine and Physiology, signaling the definitive recognition of the impact of circadian rhythms on every aspect of human health. This seminal award signified the incipience rather than the culmination of the field of Circadian Medicine.

While sleep is the most recognizable circadian rhythm, this timekeeping mechanism is a fundamental and multi-scaled organizing principle of cellular life that synchronizes our genes, proteins, metabolism, physiology, immunity, brain function and behavior with the rotation of the earth. Disruption of circadian rhythms directly impacts major human scourges including sleep disorders, Alzheimer’s disease, stroke, epilepsy, bipolar disorder, schizophrenia, autism spectrum disorders, diabetes, cancer, myocardial infarction, immune function, and infections. But the circadian clock also regulates the metabolism of drugs and the availability of drug targets. The application of circadian science to medical practice is still nascent and represents a vast suite of opportunities for integrating timing into personalized medicine, the study of human pathology, and strategies to mitigate it.

We invite submissions on the practice, promise, and theory of translating circadian biology to medicine. All medical applications from pediatrics to neurodegeneration and drug screens to biomarker development are appropriate. We welcome primary research, reviews, perspectives, or comments focused on this fourth-dimension medicine.

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Editors

The Collection will publish original research Articles, and Commentary such as Reviews, Perspectives, and Comments (full details on content types can be found here). Papers will be published in npj Biological Timing and Sleep as soon as they are accepted and then collected together and promoted on the Collection homepage. All Guest Edited Collections are associated with a call for papers and are managed by one or more of our Editorial Board Members and the journal's Editors.

This Collection welcomes submissions from all authors – and not by invitation only – on the condition that the manuscripts fall within the scope of the Collection and of npj Biological Timing and Sleep more generally. See our editorial process page for more details.

All submissions are subject to the same peer review process and editorial standards as regular npj Biological Timing and Sleep articles, including the journal’s policy on competing interests. The Guest Editor has no competing interests with the submissions, which she handles through the peer-review process. The peer review of any submissions for which the Guest Editor has competing interests is handled by another Editorial Board Member who has no competing interests. See our Collections guidelines for more details.

This Collection is not supported by sponsorship.