Extended Data Fig. 6: Detailed views of relevant regions of the holo-transpososome map and atomic model. | Nature

Extended Data Fig. 6: Detailed views of relevant regions of the holo-transpososome map and atomic model.

From: Molecular basis for transposase activation by a dedicated AAA+ ATPase

Extended Data Fig. 6

a, IstA area around the DDE motif (sharpened density map is contoured at a threshold value of 0.00865 in all panels). b, Details of some contacts between the transposase and the R1 repeat from the donor DNA (TIRR1). c, Close-up view of one of the catalytic DDE domains. d, Contacts between IstB AAA+ domain and the target DNA near IstA catalytic monomer. e, Density showing the goodness of the fit of the DNA around the insertion site. f, Detailed view of the NTDs of a central IstB dimer.

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