Extended Data Fig. 3: Acute IL-23 driven responses in IL-23R+ intestinal cells. | Nature

Extended Data Fig. 3: Acute IL-23 driven responses in IL-23R+ intestinal cells.

From: CTLA-4-expressing ILC3s restrain interleukin-23-mediated inflammation

Extended Data Fig. 3

a, Volcano plots of differentially expressed genes in scRNA-seq dataset from IL-23R+ immune cells from the small intestine of IL-23R-eGFP mice before and after IL-23 stimulation in annotated cell types. b, UMAP plots of scRNA-seq data showing indicated gene expression in different clusters before and after IL-23 stimulation (1-NKp46+ ILC3s, 2-CCR6+ ILC3s, 3-DN ILC3s, 4-γδ T cells, 5-TH17 cells, 6-Proliferative cells). The statistics was obtained by the Wilcoxon test as implemented by Seurat; red dots are significantly different.

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