Extended Data Fig. 3: Acute IL-23 driven responses in IL-23R+ intestinal cells.
From: CTLA-4-expressing ILC3s restrain interleukin-23-mediated inflammation
![Extended Data Fig. 3](https://cdn.statically.io/img/media.springernature.com/full/springer-static/esm/art%3A10.1038%2Fs41586-024-07537-3/MediaObjects/41586_2024_7537_Fig8_ESM.jpg)
a, Volcano plots of differentially expressed genes in scRNA-seq dataset from IL-23R+ immune cells from the small intestine of IL-23R-eGFP mice before and after IL-23 stimulation in annotated cell types. b, UMAP plots of scRNA-seq data showing indicated gene expression in different clusters before and after IL-23 stimulation (1-NKp46+ ILC3s, 2-CCR6+ ILC3s, 3-DN ILC3s, 4-γδ T cells, 5-TH17 cells, 6-Proliferative cells). The statistics was obtained by the Wilcoxon test as implemented by Seurat; red dots are significantly different.