Extended Data Fig. 2: Biophysical property assessment of base editable CD45 variants.
From: Selective haematological cancer eradication with preserved haematopoiesis
a, Flow cytometry of CD45 variants overexpressed in DF-1 cells affecting MIRG451 and BC8 epitopes (n = 4 biological replicates, n = 2 for Y232C). On-set temperatures (b) and monomeric content (c) of purified recombinant CD45 D1-D2 protein variants (n = 1-2).