Extended Data Fig. 1: Correlation between Tyr kinase PSSMs derived from PSPA assays and bacterial peptide display. | Nature

Extended Data Fig. 1: Correlation between Tyr kinase PSSMs derived from PSPA assays and bacterial peptide display.

From: The intrinsic substrate specificity of the human tyrosine kinome

Extended Data Fig. 1

Pearson correlation coefficients for position specific scoring matrices (PSSMs) obtained previously for five kinases screened by bacterial display7 were calculated against the PSSMs of the 78 conventional RTKs and nRTKs obtained in this study. Correlation coefficients are sorted from lowest to highest with each of the 5 kinases screened by bacterial display with the 5 best-matching kinase selectivities in our study explicitly labelled.

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