This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
![](https://cdn.statically.io/img/media.springernature.com/m312/springer-static/image/art%3A10.1038%2Fs41576-024-00752-8/MediaObjects/41576_2024_752_Fig1_HTML.png)
References
Lee-Six, H. et al. The landscape of somatic mutation in normal colorectal epithelial cells. Nature 574, 532–537 (2019).
Lorenzo-Martín, L. F. et al. Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo. Nature https://doi.org/10.1038/s41586-024-07330-2 (2024).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Competing interests
M.P.L. is shareholder in Doppl, which is commercializing patents on the scaffold-guided organoid technology used here.
Rights and permissions
About this article
Cite this article
Lorenzo-Martín, L.F., Lutolf, M.P. Mini-colons unlock tumour development outside the body. Nat Rev Genet (2024). https://doi.org/10.1038/s41576-024-00752-8
Published:
DOI: https://doi.org/10.1038/s41576-024-00752-8