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What causes long COVID? Case builds for rogue antibodies

Study finds that antibodies from people with the debilitating condition trigger similar symptoms in mice.
  1. Carissa Wong
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Antibodies isolated from people with long COVID increase pain sensitivity and reduce movement in mice when transferred to the animals, research shows1. The findings suggest that antibodies might drive some symptoms of long COVID — although how that process works is unclear, and the results will need to be replicated in larger studies.

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Nature 630, 798-799 (2024)

doi: https://doi.org/10.1038/d41586-024-02010-7

References

  1. Chen, H.-J. et al. Preprint at bioRxiv https://doi.org/10.1101/2024.05.30.596590 (2024).

  2. Zuo, W. et al. Lancet Infect. Dis. https://doi.org/10.1016/S1473-3099(24)00171-3 (2024).

    Article  Google Scholar 

  3. Kell, D. B., Laubscher, G. J. & Pretorius, E. Biochem. J. 479, 537–559 (2022).

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