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UDP-glucosamine 4-epimerase

From Wikipedia, the free encyclopedia
UDP-glucosamine 4-epimerase
Identifiers
EC no.5.1.3.16
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, an UDP-glucosamine 4-epimerase (EC 5.1.3.16) is an enzyme that catalyzes the chemical reaction

UDP-glucosamine UDP-galactosamine

Hence, this enzyme has one substrate, UDP-glucosamine, and one product, UDP-galactosamine.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is UDP-glucosamine 4-epimerase.

References

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  • MALEY F, MALEY GF (1959). "The enzymic conversion of glucosamine to galactosamine". Biochim. Biophys. Acta. 31 (2): 577–8. doi:10.1016/0006-3002(59)90047-2. PMID 13628700.
  • Silbert JE; Brown DH (1961). "Enzymic synthesis of uridine diphosphate glucosamine and heparin from [14C]glucosamine by a mouse mast-cell tumor". Biochim. Biophys. Acta. 54 (3): 590–592. doi:10.1016/0006-3002(61)90105-6. PMID 14039274.