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Mandelamide amidase

From Wikipedia, the free encyclopedia
mandelamide amidase
Identifiers
EC no.3.5.1.86
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a mandelamide amidase (EC 3.5.1.86) is an enzyme that catalyzes the chemical reaction

(R)-mandelamide + H2O (R)-mandelate + NH3

Thus, the two substrates of this enzyme are (R)-mandelamide and H2O, whereas its two products are (R)-mandelate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is mandelamide hydrolase. This enzyme is also called Pseudomonas mandelamide hydrolase.

References

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  • Yamamoto K, Oishi K, Fujimatsu I, Komatsu K (1991). "Production of R-(−)-mandelic acid from mandelonitrile by Alcaligenes faecalis ATCC 8750". Appl. Environ. Microbiol. 57 (10): 3028–32. PMC 183915. PMID 1660699.