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Alpha-humulene 10-hydroxylase

From Wikipedia, the free encyclopedia
Alpha-humulene 10-hydroxylase
Identifiers
EC no.1.14.13.150
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Alpha-humulene 10-hydroxylase (EC 1.14.13.150, CYP71BA1) is an enzyme with systematic name alpha-humulene,NADPH:oxygen 10-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

alpha-humulene + O2 + NADPH + H+ 10-hydroxy-alpha-humulene + NADP+ + H2O

Alpha-humulene 10-hydroxylase requires cytochrome P-450.

References

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  1. ^ Yu F, Okamoto S, Harada H, Yamasaki K, Misawa N, Utsumi R (March 2011). "Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis". Cellular and Molecular Life Sciences. 68 (6): 1033–40. doi:10.1007/s00018-010-0506-4. PMC 11114803. PMID 20730551. S2CID 35653829.
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