Advanced preservation reagents to power immuno-oncology and multiomics research


Wednesday 24 July 2024
8.00 PDT | 11.00 EDT | 16.00 BST | 17.00 CEST
 

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Advanced preservation reagents to power immuno-oncology and multiomics research


Wednesday 24 July 2024
8.00 PDT | 11.00 EDT | 16.00 BST | 17.00 CEST
 

Overview

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Generating high-quality single-cell data requires samples with high cell viability and minimum to no alteration of their true biological state. This is especially challenging for single-cell workflows, which often require long processing and handling times. Further complicating the above are studies that require shipping or transferring of samples across different sites and locations. Keeping these needs in mind, a novel cell preservation solution was developed that works across a variety of single-cell applications including flow cytometry, RNA-seq, CITE-seq and qPCR.

This webcast will showcase two sets of data powered by this novel cell preservation solution. First, learn how it enabled researchers to explore the tumor microenvironment (TME) and its influence on immunomodulatory agents. A novel approach to examine immune responses in the TME with small tumor samples will be presented. This approach has now helped uncover the balance of PD-1 expression between tumor-infiltrating effector cells and regulatory T (Treg) cells as a biomarker for evaluating the effects of PD-1/PD-L1 blockade immunotherapy.

The second set of data will walk through a step-by-step approach for conducting single-cell multiomics studies to generate high-quality data with preserved samples. Learn how to preserve and ship your samples for up to 72 hours at 4°C and still generate RNA-seq, CITE-seq and TCR/BCR single-cell data with confidence.

Learn how to:
  • Preserve and ship cells and tissues for multisite studies
  • Employ cell preservation technologies critical to discovery studies using tumor samples
  • Use a single preservation solution to support flow cytometry, RNA-seq and CITE-seq research

This webcast has been produced by BD Biosciences, who retain sole responsibility for content. For Research Use Only. Not for use in diagnostic or therapeutic procedures. About this content.

Presenters

Presenter
Hiroyoshi Nishikawa
Division of Cancer Immunology, Research Institute
National Cancer Center Japan
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Presenter
Cynthia Sakofsky
Staff Scientist
BD Biosciences
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Presenter
Moderator: Sarah Hiddleston
Science Journalist
Nature Research Custom Media
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