Up until recently I thought Chameleon was one of the worst Spider-Man villains, if not the worst. But his modern story/origin is crazy, as well as some of the things he has done.

Dmitri was born in Soviet Russia to a servant and the patriarch of the Russian Kravinoff family. He was the half-brother of Sergei Kravinoff, the legitimate heir, who treated Dmitri with cruelty and contempt. Dmitri's only friend was Joe Cord, an American boy who saved his life. Dmitri became a master of disguise and Soviet spy after repressing his identity and believing he was friends with Sergei. He initially used makeup, costumes, and his skills to hide his identity, but later developed a serum that allowed him to change his appearance without those aids. By doing missions as a spy/assassin, Chameleon earned his place in the Kravinoff family, unlike Sergei.

However, everything changed when he did a mission in New York City and was stopped by Spider-Man. An upstart. A kid. The fabled spy was taken out by someone like him. He lost everything and went insane with madness, a pure unbridled hatred for Spider-Man. This drove him to fully undergo the experimental surgery offered by Oscorp, and now Chameleon was a complete monster. Along with being able to turn into anyone, Chameleon has on-demand invisibility, a healing factor, high durability, a little super strength, and super speed. The most deadly thing he got was the ability to be completely un-detected by Spider-Sense. With these powers he would destroy Peter Parker’s life.