Compass Therapeutics Inc.’s Post

A new paper ''Evaluation of the Antitumor Effects of Platinum-Based [Pt(η1-C2H4-OR)(DMSO)(phen)]+ (R = Me, Et) Cationic Organometallic Complexes on Chemoresistant Pancreatic Cancer Cell Lines'' is now online. See more on Bioinorganic Chemistry and Applications Hindawi Publishing. #platinumcomplex #antitumor #citotoxicactivity 

Trastuzumab deruxtecan in HER2-positive advanced gastric cancer: exploratory biomarker analysis of the randomized, phase 2 DESTINY-Gastric01 trial https://lnkd.in/gRft7Gay #Science #MedicalAdvances

💥The following paper: "Investigational Drug Treatments for Triple-Negative Breast Cancer" is published in the Journal of Personalized Medicine MDPI at: https://lnkd.in/gUTce5aJ We invite you to read this paper at the above link. And also hope that you could consider JPM (https://lnkd.in/g3jxwN_H) when submitting your next paper. #personalizedmedicine #precisionmedicine #breastcancer

Tubulis GmbH doses first patient in phase 1/2a trial investigating #ADC candidate TUB-040 in ovarian cancer and lung adenocarcinoma (NSCLC). TUB-040 is a NaPi2b-targeting Exatecan ADC based on Tubulis’ proprietary linker technology with better biophysical properties that demonstrated effective and durable responses in a range of preclinical models. ℹ Read more: https://lnkd.in/gEZhZcaM

Trastuzumab deruxtecan in HER2-positive advanced gastric cancer: exploratory biomarker analysis of the randomized, phase 2 DESTINY-Gastric01 trial #ctDNA https://lnkd.in/dJ2xDW_b

Targeted Degradation of CDK4/6: An Innovative Approach to Overcoming Cancer Drug Resistance https://lnkd.in/guk-c6a2 ACS Med. Chem. Lett. Asap 2023. #drugdevelopment #science #medicinalchemistry #drugdiscovery #medicine #drugspharmaceuticals #oncology #drug

Our latest study is now online at Frontiers in Oncology! In our study, we identified two robust predictors for taxane-based neoadjuvant chemotherapy in ER+/HER2-breast cancer. These two predictors have a high potential for translation into the clinics both as tools that guide treatment decisions and also as drug targets. We are excited about our new projects to translate this potential! #cancerresearch #precisionmedicine #biomarkerdiscovery #breastcancer #chemoresistance #cancerchemotherapy #medicine #pharmacology #bioinformatics #datascience #GOLab #KoçUniversity #KoçUniversitySchoolofMedicine #KUSOM #KUTTAM #KoçUniversityResearchCenterforTranslationalMedicine

Karyopharm Presents Updated Exploratory Subgroup Analyses from SIENDO Study in Patients with Advanced or Recurrent TP53 Wild-Type Endometrial Cancer During 2024 ASCO Plenary Series: Rapid Abstract Updates #stockmarket #stocks #investing #businessnews #trading #daytrading

#STEAP1, a protein often overexpressed in prostate cancer, is becoming a key focus in cancer research. Understanding STEAP1's role in cancer can lead to better diagnostic tools and targeted therapies, potentially improving outcomes for patients. As research continues, STEAP1 might become a crucial component in the fight against cancer. https://lnkd.in/ehz_EPts 🧬 #CancerResearch #STEAP1 #ProstateCancer #Biomarkers #MedicalResearch

A paper in the Journal of Pharmacokinetics and Pharmacodynamics used a PBPK model to quantify the affects of drug interactions with combination breast cancer therapy (docetaxel, cyclophosphamide, and epirubicin). PBPK = physiologically based pharmacokinetic Link to Abstract: https://bit.ly/4cJlvP4 | #DrugDrugInteraction #CancerTreatments #Docetaxel #Cyclophosphamide #Epirubicin #PharmacokineticModels Springer Nature Group