Here's my take on [Nyx Prime].
Goal was, to make her survive in Steel Path, even when solo and to strip defense by 100%.
As I had problems with Acolytes sometimes, I replaced Absorb with Condemn. This makes killing them pretty easy.
Keep her 3 up all time as this will help with survivability. Recast it once you move out of the initial range.
Use 1 on heavy units to mind control them. Immediately shoot at them to buff their damage output.
Use 2 to strip all defense from up to 6 enemies. Armor and shields will be removed by 100%
Cast 4 (Condemn) on enemies you are struggeling with (e.g. Acolytes) to chain them where they are. You'll have a couple of seconds to kill them without much risk (especially if your 3 is up).
If the s..t is about to hit the fan, roll to activate rolling guard and get out of the danger zone.
Arcanes are up to you. Use whatever you like / helps you.
For this build, I mostely use the [Acceltra] as Primary, a [Kuva Nukor] as Secondary and a [Pennant] for Melee
Focus school of choice is Zenurik. Wellspring helps to avoid running out of energy. Energy is crucial as you depend on your abillities.
Companion is [Carrier Prime] with [Primed Regen] and [Sacrifice]. Just to be sure ...
I also have Magus Elevate equiped to replenisch health if needed.
This build works for me and my playstyle. I'm usually playing in public squads or solo and I'm not doing endurance runs. Usually, enemies are < lvl200.
[Augur Reach] can be relaced with [Streamline], [Flow], [Chaos Sphere] or whatever you prefer. You'll still get 40m radius without it.