![immune cells with receptors resembling male and female symbols](https://cdn.statically.io/img/media.springernature.com/w735h400/nature-cms/uploads/cms/pages/6773/top_item_image/Immunol_Hero_Jul24-6b77eec46e0b48d20b88808fa341993d.jpg)
The conneXion between sex and immune responses
Immune responses to pathogens and self-antigens show sex-based differences. Anguera and colleagues explore the role of hormones and genetics in shaping immune responses.
Immune responses to pathogens and self-antigens show sex-based differences. Anguera and colleagues explore the role of hormones and genetics in shaping immune responses.
This Review covers recent advances in our understanding of CD28 co-stimulation of T cells and discusses an emerging paradigm that positions CD28 as central to the success of current and future immunotherapeutic approaches to treating cancer.