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Beta-ketoacyl-ACP synthase I

From Wikipedia, the free encyclopedia
3-oxoacyl-[acyl-carrier-protein] synthase I
Identifiers
EC no.2.3.1.41
CAS no.9077-10-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a beta-ketoacyl-acyl-carrier-protein synthase I (EC 2.3.1.41) is an enzyme that catalyzes the chemical reaction

an acyl-acyl-carrier-protein + malonyl-acyl-carrier-protein a 3-oxoacyl-acyl-carrier-protein + CO2 + acyl-carrier-protein

Thus, the two substrates of this enzyme are acyl-acyl-carrier-protein and malonyl-acyl-carrier-protein, whereas its 3 products are 3-oxoacyl-acyl-carrier-protein, CO2, and acyl carrier protein. This enzyme participates in fatty acid biosynthesis. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups.

Nomenclature

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The systematic name of this enzyme class is acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating).

Other names in common use include:

  • beta-ketoacyl-ACP synthase I,
  • beta-ketoacyl synthetase,
  • beta-ketoacyl-ACP synthetase,
  • beta-ketoacyl-acyl carrier protein synthetase,
  • beta-ketoacyl-[acyl carrier protein] synthase,
  • beta-ketoacylsynthase,
  • condensing enzyme (CE),
  • 3-ketoacyl-acyl carrier protein synthase,
  • fatty acid condensing enzyme,
  • acyl-malonyl(acyl-carrier-protein)-condensing enzyme,
  • acyl-malonyl acyl carrier protein-condensing enzyme,
  • beta-ketoacyl acyl carrier protein synthase,
  • 3-oxoacyl-[acyl-carrier-protein] synthase,
  • 3-oxoacyl:ACP synthase I,
  • KASI,
  • KAS I,
  • FabF1, and
  • FabB.

References

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