Ranjani Sam Kumaran MS, MBA

Pointe-Claire, Quebec, Canada Contact Info
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About

Founder & Consultant at Finesse Consulting Inc., who loves helping clients realize their…

Activity

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Experience & Education

  • Finesse Consulting Inc

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Courses

  • Biomedical Device Design

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  • Biosensor Design and Application

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  • Design Engineering Experiments

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  • FDA Regulation

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  • Human System Neuroscience

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  • Introduction to Neural Engineering

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  • Low Power Bioelectronics

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  • Neural Plasticity and Neurorehabilitation

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  • Thesis

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Projects

  • Integrated Electronics design for Intracranial Pressure Measurement over ECoG grid electrodes.

    Coursework: Low Power Bioelectronics

    To Integrate ECoG electrodes sensor with a Reid based Low Noise Low Power OTA circuit. ON Semiconductor AMI Cadence 5N toolkit was used for the schematic, Virtuoso for the layout, spectre for simulation.
    Layout was incorporated onto a Bond Pad, simulated and tested.
    ComSol was used for simulations of the sensors.

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  • Rhythmic Auditory Stimulation (RAS) for PD cases - Neurorehabilitaion

    This was part of a coursework literature review, which included a proposal.
    The hypothesis or proposal here is that with a pre exposure or training with RAS before the trials may serve much better for improving the movement based on synaptic strengthening or neuroplasticity.

  • Simple, Low-cost Method to Detect Increased Intra Cranial Pressure Integrable with ECoG Electrodes

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    Specific Goals of this work:
    1) To design an intracranial pressure monitoring system
    2) To implement the system in a ICP model to comment on the efficacy of the system

  • Investigation and Validation of Symptomatic and Pathological Difference between MPP+ Injections in Caudate and Putamen

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    This a research study as part of the research credits taken. Literature Study and initial practical work was completed for this work.

    Introduction:
    Studying the functional circuits of basal ganglia helps us to understand and substantiate for the motor and cognitive disturbances related to basal ganglia such as Parkinson’s Disorder and Huntington’s Disorder. Pathological investigation along with symptomatic exploration facilitates in routing out the process of disease development…

    This a research study as part of the research credits taken. Literature Study and initial practical work was completed for this work.

    Introduction:
    Studying the functional circuits of basal ganglia helps us to understand and substantiate for the motor and cognitive disturbances related to basal ganglia such as Parkinson’s Disorder and Huntington’s Disorder. Pathological investigation along with symptomatic exploration facilitates in routing out the process of disease development. Here we are interested in injecting the non human primates with MPP+ in two different areas in the basal ganglia in two monkeys.

    Specific goals of this work:
    1) To observe and score the symptomatic difference in monkeys with putamen and caudate injected with MPP+.
    2) To observe and score the amount of dopamine depletion in Substantia Nigra, Caudate and Putamen from the brain slices of MPP+ injected monkeys.

  • Experimental Analysis Of Excercise Regimes for Optimum Weight Loss

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    Objective:
    Designing an Experiment to Obtain the most effective Excercise Regime for Optimum Weight Loss, analyzing the data collected using statistical analysis techniques provided in JMP
    Project Approach:
    -Response Variable established
    -Factors and respective Levels decided based on scientific studies and surveys
    - 2^k Full Factorial Design( 3 Factors with 2 levels each)
    -Using JMP to create the Design Table and analyze the data( Analysis of Variance, Residual Plots…

    Objective:
    Designing an Experiment to Obtain the most effective Excercise Regime for Optimum Weight Loss, analyzing the data collected using statistical analysis techniques provided in JMP
    Project Approach:
    -Response Variable established
    -Factors and respective Levels decided based on scientific studies and surveys
    - 2^k Full Factorial Design( 3 Factors with 2 levels each)
    -Using JMP to create the Design Table and analyze the data( Analysis of Variance, Residual Plots, Prediction Plots, Normal Plots etc.) obtained from test subjects.

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  • Experimental Analysis of Exercise Regimes for Optimum Weight Loss

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    A practical work with statistical analysis to figure out the best work out regimes for healthy weight-loss with minimal time frames and a constant diet to accommodate a busy work culture.
    This experiment and analysis was performed as a part of a statistical coursework.

  • LFP Activity during Visuomotor Rotation Task

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    Observed and Inferred the changes between game states, channels (electrode placement), and trials for a BCI experiment.

  • A Real Time Cough Monitor for Classification of Various Pulmonary Diseases

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    The goal of this work is to put into use of a non-invasive and unobtrusive device that will accurately record the frequency of cough. This may be used to differentiate between the pulmonary diseases (screen) based on the frequency of cough and the cough pattern.

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  • 8-Channel Touch Switch to Study The Behavioral Characteristics of Monkeys to Determine the Motor Responses

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    Purpose: To exactly find the time at which the switches are touched by the subject (monkeys). So the design requires a visual indication of touch and also computer interfacing to know the time of touch precisely for further analysis.
    Implication: This information will be useful in order to align and analyze the neural activity recorded while the monkey performs the behavioral task.

  • Correlation between two local field potential signals for gamma band activity

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    Purpose: To extract the gamma band of LFP (30-70 Hz) and look for the power of the signal to compare and contrast it from the other bands. Secondly it targets on finding the amount of coherence or relation between two such gamma bands.
    Implication: Validate previous studies

  • Continuous Body Temperature Monitoring Using LM35

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    This is a mini project designed as a part of a coursework.
    The human body temperature is detected by the wearable thermal detecting device, and then transmits the temperature signal to the comparator and the alarming circuit.

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