Increased glucose permeability in Babesia bovis-infected erythrocytes

JM Upston, AM Gero�- International journal for parasitology, 1990 - Elsevier
Glucose influx into bovine erythrocytes was found to be significantly increased upon
infection with the parasite, Babesia bovis. The influx of glucose into the infected cells over 4
min was not saturable at high concentrations of glucose (240 mm) nor was it affected by
established inhibitors of mammalian glucose transport, such as cytochalasin B and phloretin
(0.1–100 μ m). Glucose uptake into the parasitized cells was, however, inhibited by
phloridzin (phloretin-2-β-glucoside) at concentrations over the range of 10–500 μ m. Further�…
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